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Acute Lymphoblastic Leukemia (ALL): A rapidly progressive cancer that starts by the malignant transformation of a marrow lymphocyte. ALL is the most common form of childhood leukemia. The transformed, now malignant, cell multiplies and accumulates in the marrow as leukemic lymphoblasts. The lymphoblasts block normal blood cell-formation in the marrow, resulting in insufficient production of red cells, white cells and platelets. The specific chromosome and genic changes in the affected cells can be used to classify ALL. These findings can be used to determine the expected response of that type of ALL to treatment. The risk category of the ALL determined from the genic changes can affect the treatment applied. (See Society booklet "Acute Lymphocytic Leukemia")
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The Leukemia & Lymphoma Society® (LLS) is the world's largest voluntary health agency dedicated to blood cancer. The LLS mission: Cure leukemia, lymphoma, Hodgkin's disease and myeloma, and improve the quality of life of patients and their families. LLS funds lifesaving blood cancer research around the world and provides free information and support services.
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