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  LymphomaLinks - Your Link to the Latest Lymphoma News  


AUGUST 2009 800.955.4572 Email the IRC Forward to a Friend
 

Welcome to LymphomaLinks, your monthly source of lymphoma news, research updates, clinical trials and events sponsored by The Leukemia & Lymphoma Society (LLS). For even more information, regularly visit LLS's Patient Services and Disease Information Web sections.

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Latest Lymphoma News 

Study Identifies Successful New Treatment for Hodgkin's Lymphoma
A new chemotherapy regimen for pediatric Hodgkin lymphoma patients enhances efficacy through dose-dense drug delivery while simultaneously reducing the long-term risks presented by high cumulative dose chemotherapy
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LLS Features    ::READ MORE::
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Research Roundup
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IRC Question of the Month   
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Inspirational Stories

Inspirational ImageLearn how individuals touched by blood cancer cope. LLS's  LifeMosaic Web feature offers hundreds of inspiring stories by patients and families. Read them or submit your own. This month, meet David.


Here to Help

For even more information, regularly visit the LLS Web site,
www.LLS.org , where many of our education programs are archived free of charge for convenient access 24/7.

If you haven't found what you're looking for in LymphomaLinks , please call our Information Resource Center (IRC) to speak with trained information specialists. IRC staff are available Monday through Friday, 9 a.m. to 6 p.m. ET, toll free at (800) 955-4572; email
infocenter@lls.org ; or click the "Live Patient Help" button on the www.LLS.org homepage.

 

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Commentary  
Deborah Banker, Ph.D., shares more news on immunotherapies.


Clinical Trials
We invite you to use our 
LLS-supported TrialCheck® Web site, a clinical trial search service that offers patients and caregivers immediate access to listings of all lymphoma clinical trials. Answer just a few simple questions and a list of available clinical trials related to your cancer will appear in an easy to read list of search results. 

You may also want to visit the National Cancer Institute's Cancer Trials Support Unit, providing resources and information on phase III cancer treatment trials supported by the National Cancer Institute ::SELECTED TRIALS::



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Latest Lymphoma News

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Temsirolimus Effective in Some Cases of Heavily Treated Mantle Cell Lymphoma
A phase III clinical trial comparing treatments for relapsed or refractory mantle cell lymphoma indicates that temsirolimus significantly improves progression-free survival and objective response rates, compared with established chemotherapeutic agents.

Considering Longer Chemotherapy
Doctors and pharmaceutical companies are moving toward treating cancer patients with drugs continuously, even when they may not urgently need them.

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LLS Features

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My Personal Lymphoma Journey
This unique interactive Web program follows the stories and experiences of lymphoma survivors, including a new story of a follicular lymphoma survivor. The guest physician is John P. Leonard, MD, of Weill Medical College of Cornell University/New York-Presbyterian Hospital, New York, NY. We hope this program helps you to learn more about the lymphoma journey, and resources that are available to you and other lymphoma survivors.

My Clinical Trials Journey
This personalized and interactive program follows the stories and experiences of three cancer survivors who have participated in clinical trials, including a lymphoma survivor. Their stories of hope and determination are compelling. Ann Pirro, Physician's Assistant at Queens Medical Center, Fresh Meadows, NY, provides expert insights along the way.  

LLS Advocacy
LLS's advocacy team represents the needs of cancer patients and their families in Washington, DC and state capitals throughout the United States. We need your help. Join our Advocates Network and make your voice heard.

TAKE ACTION: Urge Your Representative to Support Increased Cancer Research Funding - Tell your elected officials that to win the war on cancer, they need to fund the war on cancer!
 
Patient Services Survey
Please give us your feedback by completing LLS Disease & Treatment Publications - Survey for Patients, Family and Friends.

LLS Blog

Learn the many ways you can help advance the LLS mission, including making a donation. Find out more  about our other eNewsletters.


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Research Roundup

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Mutant Protein Implicated in Diffuse Large B-cell Lymphoma ::READ MORE::

A Phase II study of SGN-30 (anti-CD30 mAb) in Hodgkin lymphoma or systemic anaplastic large cell lymphoma. ::READ MORE::

Humanized Anti-CD20 Antibody, Veltuzumab, in Refractory/Recurrent Non-Hodgkin's Lymphoma: Phase I/II Results. ::READ MORE::

A phase II trial of single agent bevacizumab in patients with relapsed, aggressive non-Hodgkin lymphoma: Southwest oncology group study S0108. ::READ MORE::

Blood-Brain Barrier Disruption and Intra-Arterial Methotrexate-Based Therapy for Newly Diagnosed Primary CNS Lymphoma: A Multi-Institutional Experience. ::READ MORE::

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Clinical Trials
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Selected Trials 

Phase II: Bendamustine Combined With Rituximab for Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma ::READ MORE::

A Phase 1-2, Multicenter, Open-Label Study of AEG35156 in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia and Indolent B-Cell Lymphomas ::READ MORE::

Safety and Efficacy of RAD001 in Patients with Velcade® Refractory Mantle Cell Lymphoma ::READ MORE::

Study of Repeat Intranodal Injection of Memgen's Cancer Vaccine, Ad-ISF35, in Subjects with Non-Hodgkin's Lymphoma (Follicular, Diffuse Large Cell, Mantle Cell, and Small Lymphocytic Lymphoma/Chronic Lymphocytic Leukemia ::READ MORE::

Phase II: Temsirolimus for Relapsed/Refractory Hodgkin's Lymphoma ::READ MORE::

A Pivotal Open-Label Trial of SGN-35 for Hodgkin Lymphoma ::READ MORE::


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IRC Question of the Month
Q&A

Q: I am scheduled to have radiation therapy as part of my treatment for lymphoma. What side effects can I expect from this form of treatment?

A: Radiation therapy, also known as radiotherapy, works by damaging the genetic material (DNA) within cells, which prevents them from growing and reproducing. Although the therapy targets cancer cells, healthy cells near the cancer cells may also be damaged. A goal of radiotherapy is to protect the healthy cells as much as possible, so that the benefit (destroying cancer cells) outweighs the risk (harming healthy cells). Side effects usually occur as a result of the radiation on tissue that contains rapidly dividing cells. This includes the hair follicles and the gastrointestinal tract lining.

Some patients may have no noticeable side effects or very mild ones. For others, there can be side effects of a type and severity that depend on the dose, location, and duration of the radiation. If radiation is given as conditioning treatment prior to stem cell transplant (total body radiation) then more intense side effects may occur. Side effects of radiation therapy may include increased fatigue, hair loss, diarrhea, nausea, loss of appetite, skin irritation and mouth sores (mucositis). Most side effects will gradually go away after the treatment is finished.  Discuss the course and effects of your treatment with your doctor and radiation therapist.

Radiotherapy may cause long-term and late effects (side effects that become apparent months or years after the completion of treatment). These effects depend on such factors as the age of the patient and the dose and location of treatment. Some potential long-term and late effects of radiation therapy are the development of a second cancer or infertility. It is important to discuss long-term and late effects with members of your oncology team before treatment begins.

During and after radiotherapy you need to get plenty of rest and follow a nutritious diet. Eating well during and after therapy will help you to cope with side effects, fight infection, rebuild healthy tissue and maintain body weight and energy.  You also need to follow your physician's advice about caring for the areas of skin that were exposed to radiation.

For more information on radiation therapy and side effects, you may access the LLS Radiation Therapy Web page. You can also view, print or order the free LLS fact sheets Long-Term and Late Effects of Treatment in Adults and Long-Term and Late Effects of Treatment for Childhood Leukemia or Lymphoma.

Please call our Information Resource Center (IRC) to speak with a trained information specialist. IRC staff are available Monday through Friday, 9 a.m. to 6 p.m. ET, toll free at (800) 955-4572. Contact us online or click the "Live Patient Help" button on the www.LLS.org homepage.

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Supported by an unrestricted
educational grant from
Allos Therapeutics, Inc Cephalon Oncology
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