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  MyelomaLinks - Your Link to the Latest Myeloma News  


JANUARY 2009 800.955.4572 Email the IRC Forward to a Friend
 

Welcome to MyelomaLinks, your monthly source of myeloma news, research updates, clinical trials and events of The Leukemia & Lymphoma Society (LLS). For even more information, regularly visit our Patient Services and Disease Information Web sections.

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Tandem Autologous Hematopoietic Cell Transplants Do Not Improve Multiple Myeloma Outcomes
Tandem autologous hematopoietic cell transplantation (AHCT) for multiple myeloma does not improve survival over that provided by single AHCT, according to the  Journal of the National Cancer Institute
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LLS Features    ::READ MORE::
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Research Roundup
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IRC Question of the Month  
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Inspirational Stories

Inspirational ImageLearn how individuals touched by blood cancer cope. LLS's LifeMosaic Web feature offers hundreds of inspiring stories by patients and families. Read them or submit your own.

Here to Help

For even more information, regularly visit the LLS Web site, www.LLS.org, where many of our education programs are archived free of charge for convenient access 24/7.

If you haven't found what you're looking for in MyelomaLinks , please call our Information Resource Center (IRC) to speak with trained information specialists. IRC staff are available Monday through Friday, 9 a.m. to 6 p.m. ET, toll free at (800) 955-4572; email
infocenter@lls.org; or click the "Live Patient Help" button on the www.LLS.org homepage.

In this new year, please consider a tax-deductible gift to LLS. Donate online today and help us make a difference in the lives of patients and their families. 

 

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Commentary
LLS's Deborah Banker, Ph.D., discusses some of the latest innovations presented at the recent American Society of Hematology annual meeting.

Clinical Trials
We invite you to use our LLS-supported TrialCheck® Web site , a clinical trial search service that offers patients and caregivers immediate access to listings of all myeloma clinical trials. Answer just a few simple questions and a list of available clinical trials related to your cancer will appear in an easy-to-read list of search results. 

You may also want to visit the National Cancer Institute's Cancer Trials Support Unit, providing resources and information on Phase III cancer treatment trials supported by the National Cancer Institute.  ::SELECTED TRIALS::



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Latest Myeloma News
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Prophylactic Acyclovir Prevents Herpes Zoster Outbreaks During Bortezomib Treatment
Patients with multiple myeloma who are receiving bortezomib therapy benefit from prophylactic acyclovir, which effectively and completely prevents reactivation of the varicella (herpes) zoster virus, according the researchers.

Pain Intensity Predicts Complexity of Cancer Pain Management
Pain intensity at initial assessment is significantly predictive of pain management complexity and length of time to stable pain control in patients with cancer, according to researchers.

Clinical Trial May Lead to More Effective Treatment for Blood Cancers
Researchers at Indiana University's Melvin and Bren Simon Cancer Center want to find a way to speed up the growth of new cells following umbilical cord blood transplants in adult patients with blood cancers.

Palonosetron Useful for Preventing Vomiting During Chemotherapy
Combined with dexamethasone, palonosetron is comparable to granisetron in preventing chemotherapy-induced nausea and vomiting in the acute phase and is superior to granisetron in the delayed phase, new research shows.

Oral Bisphosphonate Use Linked to Jaw Osteonecrosis
Oral treatment with the bisphosphonate alendronate for as little as a year increases the risk for osteonecrosis of the jaw following certain dental procedures, according to a new study. 

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LLS Features

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Milestones in Myeloma Therapy: An Update from the American Society of Hematology Annual Meeting
Register online for this free telephone education program on Tuesday, Feb. 3, 1 p.m. - 2:30 p.m. ET. 
The guest speaker is Robert Orlowski, M.D., Ph.D., director, Myeloma Section, associate professor, Departments of Lymphoma/Myeloma and Experimental Therapeutics, Division of Cancer Medicine, The University of Texas M.D. Anderson Cancer Center. Participants will have the opportunity to ask Dr. Orlwowski questions during the program. 

Co-Pay Assistance Program
Patients with myeloma who have difficulty paying for or simply cannot afford their prescription drug co-pays or health insurance premiums can now apply for up to $5,000 in assistance from LLS. 
 

LLS Advocacy
LLS's advocacy team represents the needs of cancer patients and their families in Washington, DC and state capitals throughout the United States. We need your help.
Join our Advocates Network  and make your voice heard.  Act Now! Urge Your Representative to Join the Pediatric Cancer Caucus.


The Leukemia & Lymphoma Society is committed to curing blood cancers and helping patients and their families.
Learn the many ways you can help advance LLS's mission. 

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Research Roundup

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A systematic review of Phase II trials of thalidomide/dexamethasone combination therapy in patients with relapsed or refractory multiple myeloma  ::READ MORE:: 

Treatment of newly diagnosed myeloma  ::READ MORE::


Bortezomib is associated with better health-related quality of life than high-dose dexamethasone in patients with relapsed multiple myeloma: results from the APEX study  ::READ MORE::
 

A prospective PETHEMA study of tandem autologous transplantation versus autograft followed by reduced-intensity conditioning allogeneic transplantation in newly diagnosed multiple myeloma  ::READ MORE::

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Clinical Trials
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Selected Trials

Phase II: Bortezomib, Thalidomide and Dexamethasone after Melphalan and Stem Cell Transplant in Treating Patients with Stage I, II or III Multiple Myeloma  ::READ MORE::

Phase 1/2 Study of Monoclonal Antibody to Treat Multiple Myeloma  ::READ MORE:: 

Phase IV: Lenalidomide and Dexamethasone with/without Transplant in Patients with Multiple Myeloma  ::READ MORE:: 

Trial of Romidepsin and Bortezomib for Multiple Myeloma  ::READ MORE:: 

A Study of Sativex for Pain Relief in Patients with Advanced Malignancy  ::READ MORE:: 

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IRC Question of the Month
Q&A

Q: At what age is a patient not eligible for a clinical trial?

A: All clinical trials have eligibility guidelines. These guidelines may be based on the patient's age, the type and stage of disease, previous treatment history and any co-existing medical conditions; for example, diabetes or high blood pressure.

Guidelines are sometimes called "inclusion criteria" (the characteristics of patients who may take part in the trial) and "exclusion criteria" (the characteristics of patients who cannot take part in the trial). Inclusion and exclusion criteria are used to ensure that patient participation is appropriate for the goals of the trial and to produce reliable medical research results. 

Some older patients may assume clinical trials are not for them. This is not necessarily true. Studies have shown that age alone does not reflect a person's overall health and ability to benefit from a clinical trial. Many older adults have been treated successfully in clinical trials.  According to reports, overall, patients in clinical trials receive more follow-up care and better disease and side-effect management, compared with patients receiving treatment outside of clinical trial settings. 

Nationwide participation in clinical trials by older adults is growing.  Participation across age-groups helps doctors determine if a treatment is safe and effective for people of different ages. Some trials are not appropriate for older adults or a subgroup of older adults, such as those with serious medical complications. But more trials are being offered to older adults, and there are also trials designed specifically for them. 

It is important to discuss clinical trials as an option with your doctor.  Please also contact LLS's Information Resource Center (IRC) at ( 800) 955-4572 to find out more about clinical trials and other treatment options for older adults with myeloma. You may also order the free LLS booklet Understanding Clinical Trials for Blood Cancers .

As always, we encourage patients, their families and caregivers to turn to the IRC for information and support. IRC specialists are available 9 a.m. to 6 p.m. ET. Call us with your questions at (800) 955-4572.

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educational grant from
Cephalon Oncology
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